Better skin
starts with repair.
Rejuran has become one of the most talked-about names in regenerative skincare—and for good reason.
Its c-PDRN® technology uses hydrolyzed DNA derived from salmon DNA as the foundation of professional topical products designed to support skin recovery, hydration, texture and a healthier-looking barrier.
At Lush Health, we use Rejuran Healing Essence, Healing Essence i and sterile post-treatment masks as part of selected regenerative skin treatments.
Think skin recovery—not filler.
PDRN stands for polydeoxyribonucleotide.
In Rejuran products, hydrolyzed DNA is used as a regenerative skincare ingredient intended to support the appearance of healthier, more resilient skin.
It does not create facial volume the way dermal filler does. It does not freeze muscle movement like tox. And it is not simply another moisturizer.
The focus is skin quality: recovery, hydration, texture, elasticity and support after procedures that intentionally stimulate the skin.
Better-quality skin.
Regenerative skincare at the cellular level.
PDRN has been studied for its role in tissue repair, inflammatory signaling and cellular recovery.
In skincare, Rejuran uses hydrolyzed DNA within topical professional formulations intended to support collagen-related pathways, moisture retention and the appearance of repaired, healthier skin.
That makes it particularly interesting after procedures such as microneedling, where the skin has intentionally been stimulated and is beginning a recovery response.
Rejuran supports the recovery environment. That pairing is one of the reasons we like it so much after regenerative skin treatments.
Because sometimes the skin needs help recovering well.
We use Rejuran when the goal is less about adding something to the face and more about improving the condition of the skin itself.
Recovery
Particularly useful in professional protocols after procedures that intentionally stimulate or temporarily disrupt the skin barrier.
Hydration
Rejuran's professional formulas are designed to support moisture and help skin feel more comfortable during recovery.
Texture
The goal is smoother-looking, healthier-feeling skin rather than simply covering texture with additional volume.
Resilience
Supporting the skin barrier and recovery process helps build a better foundation for long-term skin quality.
Three Rejuran tools.
Three different jobs.
We use different Rejuran professional products depending on the treatment area and where someone is in the recovery process.
Healing Essence
A professional formula containing 2% hydrolyzed DNA. We use it topically after selected treatments when the goal is hydration, recovery and overall skin-quality support.
Healing Essence i
A version specifically formulated for the delicate eye area, where skin is thinner and concerns often include fine texture, visible discoloration and loss of firmness.
Sterile Rejuran Mask
Used immediately after selected skin procedures to provide a clean, cooling, hydrating layer while freshly treated skin begins the recovery process.
The workhorse.
Healing Essence is the primary Rejuran professional product we use for broader skin treatment areas.
Rejuran describes the formula as containing 2% hydrolyzed DNA and positions it for professional post-procedure use to support hydration, texture and visible skin recovery.
The eye area gets its own formula.
The skin around the eyes is thinner and behaves differently from the rest of the face.
Healing Essence i is specifically formulated for this delicate area. Rejuran identifies concerns such as the appearance of dark circles, discoloration, fine lines, firmness and elasticity among its intended cosmetic targets.
We use it when the eye area needs regenerative skin support without pretending every under-eye concern needs filler.
The part your freshly treated skin is very happy about.
Immediately after microneedling or another appropriate regenerative skin procedure, the barrier is temporarily more vulnerable and the skin may feel warm, tight or reactive.
That is exactly when we want the products touching the skin to be intentional.
Our sterile post-treatment Rejuran mask gives us a clean, soothing, hydrating finish designed specifically for freshly treated skin.
This is where the pairing makes sense.
Microneedling intentionally creates controlled micro-injury in the skin to stimulate a repair response.
Rejuran Healing Essence is then used topically as part of the post-treatment recovery protocol.
This allows us to combine a procedure designed to stimulate renewal with topical regenerative skincare designed to support the skin as it recovers.
Explore MicroneedlingStimulate. Support. Recover.
Rejuran works best when we think about the entire treatment cycle.
Prepare
Skin is cleansed and prepared for the selected regenerative treatment.
Treat
Microneedling or another appropriate treatment is performed to stimulate the skin.
Apply Rejuran
Healing Essence or Healing Essence i is selected according to the treatment area and applied professionally after treatment.
Calm + Recover
A sterile post-treatment mask may be used to cool, hydrate and support the skin during the earliest part of recovery.
Better skin is built over time.
Regenerative skin treatments are rarely about one heroic appointment.
Rejuran Professional recommends a series approach for Healing Essence i, with multiple sessions spaced several weeks apart when optimal results are the goal.
That is also how we think about regenerative skin at Lush: treatment packages create consistency, allow the skin to move through repeated cycles of stimulation and recovery, and give us a much better opportunity to see meaningful improvement.
A plan can change the trajectory of the skin. Packages are designed around building and maintaining skin quality, not simply selling more appointments.
Not filler. Not tox. Not just skincare.
These treatments all belong in aesthetics, but they solve very different problems.
Because “salmon DNA” raises questions.
What is Rejuran?
Rejuran is a Korean regenerative skincare brand built around hydrolyzed DNA technology commonly referred to as PDRN or polynucleotide-based skincare. In the United States, Rejuran professional products are intended for topical use.
Is it really made from salmon DNA?
Rejuran's c-PDRN technology is derived from purified hydrolyzed salmon DNA. It is processed into cosmetic and professional topical formulations rather than using intact tissue.
Is Rejuran filler?
No. Rejuran Healing Essence products are not dermal fillers and are not used to create facial volume. Their role is focused on supporting skin quality and recovery.
What is the difference between Healing Essence and Healing Essence i?
Healing Essence is used more broadly across the face and other appropriate treatment areas. Healing Essence i is specifically formulated for delicate eye-area skin and targets concerns such as fine texture, visible dark circles and loss of firmness.
When do you use the sterile Rejuran mask?
We use the sterile post-treatment mask immediately after selected procedures when freshly treated skin benefits from a clean, cooling and hydrating recovery step.
Does Rejuran get injected?
Rejuran products marketed in the United States are intended for topical application. At Lush Health, Healing Essence, Healing Essence i and the post-treatment mask are used topically within professional treatment protocols.
Does it work well with microneedling?
Yes. Rejuran Professional specifically describes Healing Essence i for professional post-treatment use after procedures including microneedling. This is one of the primary ways we incorporate Rejuran into regenerative skin care.
How many treatments should I do?
The appropriate plan depends on the treatment and skin goals. Rejuran Professional describes a series of approximately three to four sessions spaced two to four weeks apart for Healing Essence i when optimal results are desired. We build treatment packages around the skin and procedure being used.
Is there downtime?
Rejuran itself is used as part of the recovery protocol. Downtime is primarily determined by the procedure it is paired with. For example, microneedling can cause temporary redness, sensitivity or swelling.
Stimulate the skin.
Then help it recover beautifully.
Rejuran gives us another way to support the part of aesthetics that matters long after the appointment is over: the quality of the skin itself.
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